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alirocumab (REGN727, SAR236553)

Also known as: SAR236553/REGN727

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Collapse Summary General Information
Company Sanofi
DescriptionHuman mAb targeting proprotein convertase subtilisin/kexin type 9 (PCSK9)
Molecular Target Proprotein convertase subtilisin/kexin type 9 (PCSK9)
Mechanism of ActionAntibody
Therapeutic ModalityBiologic: Antibody
Latest Stage of DevelopmentPhase III
Standard IndicationHypercholesterolemia
Indication DetailsTreat autosomal dominant hypercholesterolemia (ADH); Treat heterozygous familial hypercholesterolemia (heFH); Treat hypercholesterolemia; Treat primary hypercholesterolemia
Regulatory Designation

U.S. - Special Protocol Assessment (Treat hypercholesterolemia)

Partner

Regeneron Pharmaceuticals Inc.


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