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sirolimus (Rapamune)

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Company Pfizer Inc.
DescriptionRapamycin non-calcineurin antagonist immune suppressant, which targets FK506 binding protein (macrophilin-12)
Molecular Target FK506 binding protein 1A 12kDa (FKBP1A) (FKBP12)
Mechanism of ActionMammalian target of rapamycin (mTOR) kinase inhibitor
Therapeutic ModalityMacrocycle

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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