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Decoglurant (R1578, RG1578)

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Company Roche
DescriptionMetabotropic glutamate receptor subtype 2 (mGluR2) antagonist
Molecular Target Metabotropic glutamate receptor subtype 2 (mGluR2) (GRM2)
Mechanism of ActionMetabotropic glutamate receptor subtype 2 (mGluR2) antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationDepression
Indication DetailsAdjunctive treatment of major depressive disorder (MDD); Treat depression
Regulatory Designation

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