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Pyridorin, pyridoxamine

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Company NephroGenex Inc.
DescriptionInhibitor of non-enzymatic glycoxidation leading to advanced glycation end-product (AGE) formation
Molecular Target Not available
Mechanism of ActionAdvanced glycosylation endproduct (AGE) inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase III
Standard IndicationDiabetic nephropathy
Indication DetailsTreat diabetic nephropathy; Treat Type II diabetics with overt nephropathy
Regulatory Designation U.S. - Fast Track (Treat diabetic nephropathy);
U.S. - Special Protocol Assessment (Treat diabetic nephropathy)

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