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Anamorelin (ONO-7643) (formerly RC-1291)

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Company Helsinn Healthcare S.A.
DescriptionSmall molecule ghrelin agonist
Molecular Target Ghrelin receptor (GHSR)
Mechanism of ActionGrowth hormone secretagogue receptor (GHSR) agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase III
Standard IndicationCachexia
Indication DetailsTreat cachexia and anorexia in patients with advanced non-small cell lung cancer (NSCLC); Treat cachexia/anorexia in cancer patients
Regulatory Designation


Chugai Pharmaceutical Co. Ltd.; Especificos Stendhal S.A. de C.V.; Especificos Stendhal S.A. de C.V.; Gen Pharmaceuticals Inc.; Gruppo Angelini; Mundipharma International Ltd.; Ono Pharmaceutical Co. Ltd.; Specialised Therapeutics Australia Pty. Ltd.

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