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Nuedexta, dextromethorphan/quinidine (AVP-923) (formerly Neurodex)

Also known as: formerly Zenvia

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Company Otsuka Pharmaceutical Co. Ltd.
DescriptionCombination of the NMDA receptor antagonist dextromethorphan with quinidine sulfate, a cytochrome P450 2D6 enzyme inhibitor
Molecular Target NMDA receptor ; Sigma-1 receptor
Mechanism of ActionCytochrome P450 inhibitor; NMDA receptor antagonist
Therapeutic ModalitySmall molecule: Combination

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