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Ryzolt, Tridural, tramadol (NS-24)

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Company Endo International plc
DescriptionOnce-daily mu opioid receptor (MOR) agonist and monoamine reuptake inhibitor
Molecular Target Mu opioid receptor (MOR) (OPRM1) ; Monoamine transporters
Mechanism of ActionMonoamine reuptake inhibitor; Mu opioid receptor agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationPain
Indication DetailsTreat cancer pain; Treat chronic non-cancer pain; Treat moderate to severe low back pain; Treat moderate to severe pain; Treat moderate to severe pain associated with osteoarthritis (OA) of the knee; Treat pain
Regulatory Designation
PartnerNippon Shinyaku Co. Ltd.;
Purdue Pharma L.P.;
Valeant Pharmaceuticals International Inc.;
Whanin Pharmaceutical Co. Ltd.

 Product Details
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Total Number of DealsTotal Deal ValueTotal Upfront CashTotal Milestone Payments

1

$19.5M

$19.5M

0


 Deals Details
DateCompanies InvolvedDeal HeadlineTotal Deal ValueTotal Upfront CashTotal Milestone

10/17/2011

$19.5M

$19.5M

0

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