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Movantik, Naloxegol (Moventig) (formerly NKTR-118)

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Collapse Summary General Information
Company Nektar Therapeutics
DescriptionPEGylated form of naloxol, a peripheral mu opioid receptor (OPRM1; MOR) antagonist
Molecular Target Mu opioid receptor (OPRM1) (MOR)
Mechanism of ActionOpioid receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentApproved
Standard IndicationConstipation
Indication DetailsTreat opioid-induced constipation (OIC)
Regulatory Designation

U.S. - Undisclosed Review (Treat opioid-induced constipation (OIC));
EU - Standard Review (Treat opioid-induced constipation (OIC));
Canada - Standard Review (Treat opioid-induced constipation (OIC))

Partner

AstraZeneca plc


 Product Details
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