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Movantik, Naloxegol (Moventig) (formerly NKTR-118)

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Collapse Summary General Information
Company Nektar Therapeutics
DescriptionPEGylated form of naloxol, a peripheral mu opioid receptor (OPRM1; MOR) antagonist
Molecular Target Mu opioid receptor (MOR) (OPRM1)
Mechanism of ActionOpioid receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationConstipation
Indication DetailsTreat opioid-induced constipation (OIC)
Regulatory Designation

U.S. - Undisclosed Review (Treat opioid-induced constipation (OIC));
EU - Standard Review (Treat opioid-induced constipation (OIC));
Canada - Standard Review (Treat opioid-induced constipation (OIC))

Partner

AstraZeneca plc; Daiichi Sankyo Co. Ltd.


 Product Details
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Collapse Summary Deals Information
Total Number of DealsTotal Deal ValueTotal Upfront CashTotal Milestone Payments

2

$2,330.0M

$325.0M

$2,005.0M


 Deals Details
DateCompanies InvolvedDeal HeadlineTotal Deal ValueTotal Upfront CashTotal Milestone
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