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trimetrexate glucuronate

Also known as: NeuTrexin, trimetrexate

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Company AstraZeneca plc
DescriptionDihydrofolate reductase (DHFR) inhibitor
Molecular Target Dihydrofolate reductase (DHFR)
Mechanism of ActionDihydrofolate reductase (DHFR) inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationPneumonia
Indication DetailsTreat moderate to severe Pneumocystis carinii pneumonia(PCP) in immunocompromised patients; Treat Pneumocystis carinii pneumonia (PCP) infection
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