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Naloxegol (formerly NKTR-118)

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Company Nektar Therapeutics
DescriptionPEGylated form of naloxol, a peripheral mu opioid receptor (OPRM1; MOR) antagonist
Molecular Target Mu opioid receptor (OPRM1) (MOR)
Mechanism of ActionOpioid receptor antagonist
Latest Stage of DevelopmentPhase III
IndicationConstipation
Partner

AstraZeneca plc


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