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actoxumab/bezlotoxumab (MDX-066/MDX-1388) (MK-3415A)

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Company Bristol-Myers Squibb Co.
DescriptionCombination of bezlotoxumab, a human mAb targeting Clostridium difficile toxin B (TcdB), and actoxumab, a human mAb targeting TcdA
Molecular Target Clostridium difficile toxin B (TcdB) ; Clostridium difficile toxin A (TcdA)
Mechanism of ActionAntibody
Therapeutic ModalityBiologic: Antibody
Latest Stage of DevelopmentPhase III
Standard IndicationClostridium
Indication DetailsTreat Clostridium difficile infection (CDI)
Regulatory Designation
PartnerMerck & Co. Inc.

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