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Menadione Topical Lotion (MTL)

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Company Spectrum Pharmaceuticals Inc.
DescriptionTopical formulation of menadione (vitamin K3) that activates epidermal growth factor (EGF) receptor signaling pathway by inhibiting phosphatase activity
Molecular Target Epidermal growth factor receptor (EGFR)
Mechanism of ActionPhosphatase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationItch
Indication DetailsPrevent and treat skin rash associated with systemic treatment with epidermal growth factor receptor (EGFR) inhibitors
Regulatory Designation
Partner

 Product Details
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Total Number of DealsTotal Deal ValueTotal Upfront CashTotal Milestone Payments

1

$207.4M

$11.3M

$195.0M


 Deals Details
DateCompanies InvolvedDeal HeadlineTotal Deal ValueTotal Upfront CashTotal Milestone

07/17/2013

$207.4M

$11.3M

$195.0M

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