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tipelukast (MN-001) (formerly KCA-757)

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Company Kyorin Pharmaceutical Co. Ltd.
DescriptionLeukotriene receptor antagonist and an inhibitor of phosphodiesterase-4 (PDE-4), 5-lipoxygenase (ALOX5; 5-LO) and thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor
Molecular Target Phosphodiesterase-4 (PDE-4) ; Thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor
Mechanism of Action5-lipoxygenase inhibitor; Phosphodiesterase-4 (PDE-4) inhibitor; Thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist
Therapeutic ModalitySmall molecule

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