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mifamurtide (L-MTP-PE, Mepact) (formerly Junovan)

Also known as: MTP-PE

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Company Takeda Pharmaceutical Co. Ltd.
DescriptionMuramyl tripeptide phosphatidylethanolamine
Molecular Target Caspase recruitment domain family member 15 (CARD15) (NOD2)
Mechanism of ActionImmune modulation
Therapeutic ModalityBiologic
Latest Stage of DevelopmentMarketed
Standard IndicationBone cancer
Indication DetailsTreat high-grade resectable non-metastatic osteosarcoma after macroscopically complete surgical resection in combination with postoperative multi-agent chemotherapy; Treat lung metastases from progression of osteosarcoma; Treat newly diagnosed, resectable non-metastatic osteosarcoma; Treat non-metastatic resectable osteosarcoma; Treat osteosarcoma
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