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IV APX001

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Company Eisai Co. Ltd.
DescriptionIV formulation of a small molecule that inhibits fungal enzyme GPI-anchored wall transfer protein 1 (GWT1)
Molecular Target A. fumigatus GPI-anchored wall transfer protein 1 (A. fumigatus GWT1) ; C. albicans GPI-anchored wall transfer protein 1 (C. albicans GWT1)
Mechanism of ActionAntifungal agent
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase I
Standard IndicationFungal infection
Indication DetailsTreat coccidioidomycosis; Treat fungal infections; Treat invasive aspergillosis; Treat invasive candidiasis
Regulatory Designation U.S. - Orphan Drug (Treat coccidioidomycosis);
U.S. - Orphan Drug (Treat fungal infections);
U.S. - Orphan Drug (Treat invasive aspergillosis);
U.S. - Orphan Drug (Treat invasive candidiasis);
U.S. - Qualified Infectious Disease Program (Treat coccidioidomycosis);
U.S. - Qualified Infectious Disease Program (Treat invasive aspergillosis);
U.S. - Qualified Infectious Disease Program (Treat invasive candidiasis)
PartnerAmplyx Pharmaceuticals Inc.

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