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Company ImmunoGen Inc.
DescriptionAntibody-drug conjugate (ADC) consisting of Z4681A, a humanized anti-CD33 antibody, conjugated to DGN462, a DNA-alkylating indolino-benzodiazepine
Molecular Target CD33
Mechanism of ActionAntibody-drug conjugate
Therapeutic ModalityBiologic: Antibody-drug conjugate
Latest Stage of DevelopmentPhase I
Standard IndicationAcute myelogenous leukemia (AML)
Indication DetailsTreat CD33-positive acute myelogenous leukemia (AML)
Regulatory Designation

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