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CTL019 (formerly CART-19)

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Company Novartis AG
DescriptionAutologous T cells loaded with a lentiviral vector expressing CART-19, which consists of a cancer antigen-binding domain targeting CD19 linked to CD3-zeta/CD137 immunostimulatory domains
Molecular Target CD19
Mechanism of ActionCell therapy
Therapeutic ModalityCell therapy: Lentivirus

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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