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Stool DNA colorectal cancer screening assay (Cologuard)

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Company Exact Sciences Corp.
DescriptionNon-invasive stool DNA test that utilizes a multiplexed quantitative Invader assay for the simultaneous detection of methylated and unmethylated sequences in the promoter region of the vimentin (VIM) gene
Molecular Target Vimentin (VIM)
Mechanism of ActionDiagnostic
Therapeutic ModalityDiagnostics: Other diagnostic technologies
Latest Stage of DevelopmentMarketed
Standard IndicationCancer, Diagnostic
Indication DetailsDetect colorectal cancer and precancerous adenomas; Detection of advanced colon adenoma
Regulatory Designation U.S. - Undisclosed Review (Detect colorectal cancer and precancerous adenomas)
Partner Ironwood Pharmaceuticals Inc.

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