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Clonidine Lauriad (Validive) (BA-028)

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Company Onxeo S.A.
DescriptionMucoadhesive formulation of clonidine, an adrenergic receptor alpha 2 (ADRA2) agonist
Molecular Target Adrenergic receptor alpha 2 (ADRA2)
Mechanism of ActionAdrenergic receptor alpha 2 (ADRA2) agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationMucositis
Indication DetailsPrevent radiotherapy-induced oral mucositis in head and neck cancer patients; Treat and prevent oral mucositis induced by radiotherapy and/or chemotherapy in cancer patients; Treat and prevent oral mucositis induced by radiotherapy and/or chemotherapy in head and neck cancer patients
Regulatory Designation U.S. - Fast Track (Treat and prevent oral mucositis induced by radiotherapy and/or chemotherapy in cancer patients);
EU - Orphan Drug (Prevent radiotherapy-induced oral mucositis in head and neck cancer patients)
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