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NanoBUP (buprenorphine/naloxone)

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Company Nanotherapeutics Inc.
DescriptionCapsule containing a fixed-dose combination (4:1) of buprenorphine and naloxone
Molecular Target Mu opioid receptor (MOR) (OPRM1) ; Kappa opioid receptor (KOR) (OPRK1)
Mechanism of ActionMu opioid receptor agonist/antagonist; Opioid receptor antagonist; Kappa opioid receptor antagonist
Therapeutic ModalitySmall molecule: Combination
Latest Stage of DevelopmentPhase I
Standard IndicationAddiction
Indication DetailsTreat opiate dependence
Regulatory Designation

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