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Azedra (Ultratrace I-131-MIBG, Ultratrace iobenguane I 131)

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Company Progenics Pharmaceuticals Inc.
DescriptionRadiolabeled norepinephrine analog
Molecular Target Norepinephrine transporter
Mechanism of ActionRadiolabelled protein
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationNeuroendocrine tumors
Indication DetailsTreat malignant relapsed/refractory pheochromocytoma; Treat neuroendocrine tumors; Treat pheochromocytoma; Treat refractory high-risk neuroblastoma
Regulatory Designation

U.S. - Fast Track (Treat neuroendocrine tumors);
U.S. - Orphan Drug (Treat neuroendocrine tumors);
U.S. - Special Protocol Assessment (Treat malignant relapsed/refractory pheochromocytoma)

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