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Arimidex, anastrozole

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Company AstraZeneca plc
DescriptionAromatase inhibitor that suppresses estrogen synthesis
Molecular Target Aromatase
Mechanism of ActionAromatase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationBreast cancer
Indication DetailsAdjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer; Prevent breast cancer in postmenopausal women aged 40-70; Treat advanced breast cancer; Treat hormone-receptive advanced breast cancer as first-line therapy; Treat postmenopausal patients with hormone-sensitive early breast cancer; Treat postmenopausal patients with hormone-sensitive early breast cancer following surgery; Treat postmenopausal women with early-stage breast cancer; Treat premenopausal patients with hormone receptor-positive, recurrent/metastatic breast cancer
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