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crisaborole (formerly AN2728)

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Company Anacor Pharmaceuticals Inc.
DescriptionTopical borinic acid ester that inhibits phosphodiesterase-4 (PDE-4) and the production of tumor necrosis factor (TNF) alpha, IL-12 and IL-23
Molecular Target Phosphodiesterase-4 (PDE-4) ; Tumor necrosis factor (TNF) alpha
Mechanism of ActionPhosphodiesterase-4 (PDE-4) inhibitor
Therapeutic ModalitySmall molecule

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