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Aloxi, Onicit, Paloxi, palonosetron

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Company Helsinn Healthcare S.A.
DescriptionSelective serotonin (5-HT3) receptor antagonist
Molecular Target Serotonin (5-HT3) receptor
Mechanism of ActionSerotonin (5-HT3) receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationEmesis
Indication DetailsPrevent acute nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy in patients ages 1 month to <17 years; Prevent chemotherapy-induced nausea and vomiting (CINV); Prevent chemotherapy-induced nausea and vomiting (CINV) in pediatric patients; Prevent post-operative nausea and vomiting (PONV); Treat chemotherapy-induced nausea and vomiting (CINV)
Regulatory Designation

U.S. - Undisclosed Review (Prevent chemotherapy-induced nausea and vomiting (CINV) in pediatric patients)

Partner

Eisai Co. Ltd.; Lee's Pharmaceutical Holdings Ltd.; Taiho Pharmaceutical Co. Ltd.


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