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ALKS 5461

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Company Alkermes plc
DescriptionCombination of samidorphan (ALKS 33), a mu opioid receptor (OPRM1; MOR) antagonist, and buprenorphine
Molecular Target Mu opioid receptor (MOR) (OPRM1) ; Kappa opioid receptor (KOR) (OPRK1)
Mechanism of ActionMu opioid receptor agonist; Kappa opioid receptor antagonist
Therapeutic ModalitySmall molecule

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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