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Alimta, pemetrexed

Also known as: LY231514, MTA

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Company Eli Lilly and Co.
DescriptionAntifolate that inhibits thymidylate synthase, dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT)
Molecular Target Dihydrofolate reductase (DHFR) ; Glycinamide ribonucleotide formyltransferase (GARFT)
Mechanism of ActionDihydrofolate reductase (DHFR) inhibitor; Glycinamide ribonucleotide formyltransferase (GARFT) inhibitor
Therapeutic ModalitySmall molecule

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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