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dalantercept (ACE-041)

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Company Acceleron Pharma Inc.
DescriptionAngiogenesis inhibitor that binds to and prevents members of the transforming growth factor (TGF) beta superfamily from signaling through activin receptor-like kinase 1 (ACVRL1; ALK1; HHT2)
Molecular Target Activin receptor-like kinase 1 (ACVRL1) (ALK1) (HHT2)
Mechanism of ActionAngiogenesis inhibitor; Activin receptor-like kinase 1 (ALK1) antagonist
Therapeutic ModalityBiologic: Protein

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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