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Exviera, dasabuvir (ABT-333)

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Company AbbVie Inc.
DescriptionNon-nucleoside HCV NS5B polymerase inhibitor
Molecular Target HCV NS5B polymerase
Mechanism of ActionNon-nucleoside polymerase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentApproved
Standard IndicationHepatitis C virus (HCV)
Indication DetailsTreat chronic HCV genotype 1 infection; Treat chronic HCV genotype 1 infection in treatment-naïve patients with severe renal impairment; Treat chronic HCV genotype 1b infection in patients with compensated liver cirrhosis; Treat HCV genotype 1 infection; Treat HCV genotype 1and 4 infection
Regulatory Designation U.S. - Fast Track (Treat HCV genotype 1 infection);
EU - Standard Review (Treat HCV genotype 1 infection)

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