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Abilify Maintena (Aripiprazole depot, Once-monthly aripiprazole)

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Company Otsuka Pharmaceutical Co. Ltd.
DescriptionOnce-monthly intramuscular depot formulation of aripiprazole, a small molecule partial agonist of the dopamine D2 and serotonin (5-HT1A) receptors and antagonist of the serotonin (5-HT2A) receptor
Molecular Target Dopamine D2 receptor ; Serotonin (5-HT) receptor
Mechanism of ActionDopamine D2 receptor agonist; Serotonin (5-HT) receptor agonist/antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationSchizophrenia
Indication DetailsMaintenance treatment of schizophrenia; Treat patients in the acute phase of schizophrenia; Treat schizophrenia in acutely relapsed adults; Treat schizophrenia in pediatric patients
Regulatory Designation
Partner H. Lundbeck A/S

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