Thursday, January 10, 2013
A Memorial Sloan-Kettering Cancer Center team has
conducted one of the first large-scale screens of a small molecule library
using patient-derived induced pluripotent stem cells.1 The approach
was applied to neuronal cells derived from patients with familial dysautonomia
and provides early evidence of its potential for identifying new leads.
Kotz, J. SciBX 6(1); doi:10.1038/scibx.2013.4 Published online Jan.
1. Lee, G. et al. Nat.
Biotechnol.; published online Nov. 25, 2012; doi:10.1038/nbt.2435 Contact:
Lorenz Studer, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer
Center, New York, N.Y. e-mail: email@example.com Contact:
Gabsang Lee, The Johns Hopkins University School of Medicine, Baltimore, Md.
2. Lee, G. et al.
Nature 461, 402-406 (2009)
AND INSTITUTIONS MENTIONED
Boston Children's Hospital, Boston, Mass.
Broad Institute of MIT and Harvard, Cambridge, Mass.
Harvard Medical School, Boston, Mass.
Innovative Medicines Initiative, Brussels, Belgium
Massachusetts General Hospital, Boston, Mass.
Memorial Sloan-Kettering Cancer Center, New York, N.Y.
(SIX:ROG; OTCQX:RHHBY), Basel, Switzerland
University of Oxford, Oxford, U.K.