BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Mastermind like transcriptional coactivator 1 (MAML1); Notch 1 (NOTCH1)

April 28, 2016 7:00 AM UTC

In vitro, cell and zebrafish studies identified a thiazolidinedione-based MAML1 inhibitor that could help treat NOTCH1-dependent cancers. In silico screening of small molecule libraries and in vitro t...