ARTICLE | Distillery Therapeutics
Therapeutics: Protein inhibitor of activated STAT protein 1 (PIAS1); huntingtin (HTT)
April 21, 2016 7:00 AM UTC
Mouse studies suggest inhibiting PIAS1 could help treat HD. In a mouse model of HD, intrastriatal injection of a viral vector encoding a PIAS1-targeting microRNA (miRNA) decreased striatal levels of m...