Therapeutics: Tumor necrosis factor (TNF) receptor superfamily member 17 (TNFRSF17; BCMA; CD269)

In vitro and mouse studies suggest a bispecific antibody targeting CD3 and TNFRSF17 could help treat MM. In co-culture of T cells and TNFRSF17-expressing MM cells, the bispecific antibody bound CD3 on...