Indication

Target/marker/pathway

Summary

Licensing status

Publication and contact information

Neurology

Stroke

Not applicable

Rat studies suggest ceria nanoparticles could help treat stroke. In rats, i.v. injection of nanoparticles incorporating cerium ions after induction of ischemic stroke decreased infarct volume compared with saline injection. Next steps include determining the therapeutic window for ceria nanoparticle-mediated protection against stroke in rats and evaluating efficacy and toxicity in large animals.

SciBX 5(40); doi:10.1038/scibx.2012.1060
Published online Oct. 11, 2012

Patent application filed; available for licensing

Kim, C.K. et al. Angew. Chem. Int. Ed.; published online Sept. 11, 2012;
doi:10.1002/anie.201203780
Contact: Taeghwan Hyeon, Seoul National University, Seoul, South Korea
e-mail:
thyeon@snu.ac.kr

Contact: Seung-Hoon Lee, same affiliation as above
e-mail:
sb0516@snu.ac.kr