ARTICLE | Distillery Techniques
Techniques: Low-affinity chimeric antigen receptor (CAR) T cells to limit off-target effects of immunotherapy
November 5, 2015 8:00 AM UTC
Studies in mice suggest CAR T cells with low affinity for tumor-associated antigens could treat cancer with fewer off-target effects than high-affinity CAR T cells. In two studies, pairs of CAR T cell...