Thursday, July 17, 2014
Publication and contact
Chemically defined medium
for generation of human cardiomyocytes from induced pluripotent stem (iPS)
A chemically defined medium
for differentiating human iPS cells into cardiomyocytes could be useful for
generating cell-replacement therapies for cardiac repair. The culture medium
consists of RPMI 1640, l-ascorbic
acid 2-phosphate and rice-derived recombinant human albumin. The medium was
able to generate sheets of cardiomyocytes with a yield of up to 100
cardiomyocytes per human iPS cell. The resulting human cardiomyocytes were
not fully differentiated but still showed cardiomyocyte-like
electrophysiological behaviors and expressed multiple cardiomyocyte markers.
Next steps could include optimizing the culture medium and associated
protocols to further mature the cardiomyocytes.
Published online July 17, 2014
Patent and licensing status
Burridge, P.W. et al.
Nat. Methods; published online June 15, 2014;
Contact: Joseph C. Wu, Stanford University School of
Medicine, Stanford, Calif.
Contact: Paul W. Burridge,
same affiliation as above
All contents Copyright © 1993-2016 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement
. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions
. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
close [ X ]