Thursday, April 24, 2014
Publication and contact
Assays & screens
Detection of Plasmodium
falciparum or Trypanosome infection with ultrasound-based separation of
red blood cells (RBCs)
separation technique could help detect low levels of parasitemia. The
densities of RBCs infected with
P. falciparum are known to be lower than those of uninfected RBCs. A
handheld device was constructed that exposed a human blood droplet to
ultrasonic waves to induce density-based separation of infected RBCs and
allow for sample extraction for microscopic analysis. Compared with no
separation, the technique increased infected cell levels in samples by over
100-fold and enabled detection of Trypanosoma cyclops and the ring
stage of P. falciparum at levels corresponding to 6 parasites/mL and
25 parasites/mL. Ongoing work includes optimizing the technology
for P. falciparum detection.
Published online April 24, 2014
Patented by the University of Glasgow;
licensed to SAW Dx Ltd.
Bourquin, Y. et al.
Angew. Chem. Int. Ed.; published online March 26, 2014;
Contact: Jonathan M. Cooper, University of Glasgow, Glasgow,
All contents Copyright © 1993-2017 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement
. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions
. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
close [ X ]