Leveling cancer with IL-15

Initial excitement about using IL-15 as a therapeutic in cancer has been tempered by substantial delivery and efficacy issues. Now, data from an Institut National de la Santé et de la Recherche Médicale-led team showing that IL-15 stimulates T cell proliferation inside tumors suggests that the cytokine could help boost the potency of checkpoint inhibitors and other immunotherapies that harness T cells to attack cancer cells.¹

The data also highlight IL-15 as a potential prognostic biomarker for predicting patient outcomes in colorectal cancer and other malignancies...