Scientists doing target discovery and validation soon will be getting access to a low-cost repository of cloned cDNAs courtesy of Harvard Medical School and an as yet unnamed consortium of academic and corporate partners. The repository will raise the bar for companies that sell genomic databases, clones and expression systems.

Determining the function of all proteins is going to be a lot more difficult than determining the sequence of the genome. The Harvard Institute of Proteomics (HIP) plans to help speed the process by creating the non-profit FlexGene (full length expression) repository, which will contain physical clones of all known genes and predicted open reading frames (ORFs) from