BioCentury
ARTICLE | Tools & Techniques

Isis advances to oral antisense

April 16, 2001 7:00 AM UTC

Isis advances to oral antisense

Isis Pharmaceuticals Inc. has been working on antisense drugs for 11 years, gradually improving the chemistry of the antisense DNA. But antisense DNA is even more susceptible to enzymatic degradation than proteins, which had made systemic delivery challenging and oral delivery impossible...