BioCentury
ARTICLE | Tools & Techniques

Targretin's side effects

April 12, 1999 7:00 AM UTC

Targretin's side effects Ligand Pharmaceuticals Inc. says it is not worried about the potential side effect of hypothyroidism seen with its Targretin bexarotene and as well as other retinoid X receptor ( RXR ) selective ligands.

With both capsule and gel formulations of Targretin scheduled for NDA submissions this year to treat cutaneous T cell lymphoma (CTCL), LGND considers the issue to be less of a priority than the potential interest reviewers might have in side effects relating to triglyceride levels...