Proteomics

The ideal drug discovery program would quickly pinpoint the proteins that are responsible for, or defective in, a given disease. Genomics has dominated recent drug discovery efforts, but now several companies are touting proteomics as a more relevant technology, raising the question of which is the better starting point for target identification, genes or proteins?

Proteomics is to protein biochemistry what genomics is to molecular biology: just as genomics seeks to profile the identity and amount of every gene expressed in a given cell, proteomics seeks to profile the identity, amount, and post-translational modifications of every protein synthesized in a cell...