Graying leadership at FDA's Center for Drug Evaluation and Research, combined with a sclerotic hiring process, threatens to create a leadership vacuum at the center, according to Richard Moscicki, deputy director for science operations.

"These positions have been opening up as there has been a graying of the leadership at CDER, with people stepping away to pursue other things or to retire," he told BioCentury. Failing to bring in experienced managers "could bring us to a real crisis in leadership if we don't replenish - and replenish now."