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Product Discovery & Development
After CO-101 blowup, Clavis hopes elacytarabine produces Phase III win in 1Q13
Clavis counting on PK
Monday, November 19, 2012
The pivotal failure of CO-101 from Clovis
Oncology Inc. and Clavis
Pharma ASA led investors to hammer both stocks, as the U.S. company lost
its lead program, which used Lipid Vector technology from its Norwegian
partner. But the outcome may be more a reflection of the failure of the
biological hypothesis underlying that particular trial than of the technology
As a result, Clavis hopes its
second shot on goal, elacytarabine, still can succeed in Phase III because of a
significant pharmacokinetic advantage over the parent drug.
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