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Product Discovery & Development
Resverlogix looking to plaque regression data for RVX-208 for atherosclerosis
Rethinking HDL
By Jennifer Rhodes
Staff Writer
Published on
Monday, September 10, 2012
Now that Resverlogix
Corp. has shown positive data in the Phase IIb SUSTAIN trial of RVX-208
to treat atherosclerotic cardiovascular disease, the company is looking to data
next half from another Phase IIb trial to show that longer term dosing of
RVX-208 actually removes plaque.
RVX-208 met the primary
endpoint of increasing HDL-C from baseline to week 24 vs. placebo in SUSTAIN.
The study enrolled 176 patients with either stable or acute coronary artery
disease (CAD) and low HDL-C who were receiving statins (p=0.001).
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