BioCentury on BioBusiness,
Product Discovery & Development
Monday, July 31, 2006
The three main objectives of enrichment designs are reducing "noise" that interferes with the interpretation of results, second is improving the ratio of responders to nonresponders and third is increasing the proportion of participants who are likely to demonstrate the endpoints being studied. Complementary adaptive methods can be used to identify and enrich for responders, or to withdraw nonresponders from the test therapy.
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