BioCentury on BioBusiness,
Product Discovery & Development
Putting protease data in their place
Monday, October 6, 1997
Long-term data on viral resistance to HIV protease inhibitors may have
surprised investors last week, but it wasn't unexpected, now that PIs have been used for
long enough to begin generating such data. And it's exactly what doctors need in order to
optimize their treatment regimens.
What made things tough for Agouron Pharmaceuticals Inc. (AGPH, San
Diego, Calif.), whose Viracept was the topic of much discussion, was that negative data
from a poorly designed study came out first, followed two days later by positive data from
better-designed trials. In fact, the overall message from the week was supportive of the
early addition of Viracept to treatment combinations.
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