WASHINGTON - A paper released on Friday at a "Town Meeting on Clinical Research", conducted by the Institute of Medicine of the National Academy of Sciences, argues that health maintenance organizations, insurance programs and governments should not pay for investigational treatments.

In the article, which will appear in the July 16 issue of the Journal of the American Medical Association (JAMA), David Eddy of Kaiser Health Plan and Permanente Medical Group of Southern California argues that requiring insurers to pay for investigational treatments drives up costs; can lead to demands for coverage of frivolous or harmful products; and removes an important incentive for