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Hookipa's Vaxwave vaccine vectors to avoid adjuvants, boosters
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Hookipa: Next wave vector
Monday, April 1, 2013
Biotech AG is using its Vaxwave technology to discover and develop
viral vectors designed to elicit B cell and CD8+ T cell
immune responses without concurrent induction of antibodies that block vector
A number of companies have
developed vaccine vectors based on viruses, but the method has several
challenges, including high seroprevalence rates of the viruses from which the
vectors are derived and vector-specific antibody immunity. The former can
interfere with the efficacy of the initial vaccine administration while the
latter can prevent effective boosting.
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