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Oncorena targets RCC metastases; but faces cost-benefit challenges
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Oncorena: Metastatic destruction
Monday, January 21, 2013
Oncorena AB is banking on the specificity of orellanine for
killing kidney cells anywhere in the body to prolong survival in patients with
metastatic renal cell carcinoma. But the probable side effects mean the company
will be challenged to show any survival benefit outweighs the drug's impact on
quality of life and heath economics.
Oncorena's orellanine is a
toxin derived from the Cortinarius genus of mushrooms. According to
Executive Chairperson Sara Pellme, the molecule's potential use in RCC
was discovered at the University of Gothenburg during a search for an
antidote to the mushroom toxin.
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